1 · Sample preparation
- The patient's DNA is extracted from blood using DNA isolation kits
EUROArray
DNA microarray diagnostics
DNA microarrays consist of DNA sequences (probes) applied to a solid carrier such as glass in microscopically small spots at defined positions. When a patient's DNA contains segments that match the probes, the complementary regions hybridize. This binding is read by computer and evaluated as a positive signal.
Features
2 · Amplification (PCR)
- The target DNA sections are amplified million-fold by polymerase chain reaction
- Two primers define the region to be copied; if the target sequence is present it is copied exponentially
- PCR products are labelled with a fluorescent dye for detection on the microarray
3 · Microarray hybridization
- PCR products are mixed with hybridization buffer and incubated with the microarray
- Binding to complementary probes is measured via the fluorescence signals of the spots
Catalogues and brochures
Make inquiry
Interested in EUROArray?
Send your request and our team will get back to you with a quote, delivery time and training details.
- Phone
- +383 49 891 333
- info@swissmed-ks.com
